Why can cancers suddenly develop resistance to personalized medicine? - interview with Professor Paul Mischel, MD

In this episode, Professor Birgitte Regenberg interviews Professor Paul Mischel from Stanford University on his life as a cancer researcher and how circular DNA plays a role in cancer.

In this episode we will be talking about how Paul Mischel got into his field of research and answer a number of questions like, why are certain cancers rapidly adapting to chemotherapy treatments? How has the field of molecular biology changed cancer research? Why is circular DNA important to ongoing cancer research? How do you bring new research to market where it can benefit the patients? And finally, how can research like the kind performed in the CIRCULAR VISION project come to benefit cancer patients in the future?


Part 1 – Why is circular DNA central to cancer research?

Part 2 – Why can cancers quickly develop resistance to treatments?

Part 3 – How can fundamental research be commercialized to benefit patients?


Professor Paul Mischel MD of Stanford University is a physician scientist trained in pathology and cancer biology. He is Vice Chair of Research for the Department of Pathology as well as an Institute Scholar of ChEM-H at Stanford that also studies the role of circular DNA in cancer.

See more about Professor Paul Mischel at Stanford University, Boundless Bio and X (Twitter).

Professor Professor Birgitte Regenberg of Copenhagen University is a pioneer and expert in the field of extrachromosomal circular DNA (eccDNA) and is the coordinator of the CIRCULAR VISION project researching circular DNA as a biomarker in cancer and IBD.

See more about Birgitte Regenberg at Copenhagen University, Regenberg Lab and X (Twitter).

PODCAST: ESTRID HØGDALL - Direktør for Regionerner Bio-og GenomBank

Third episode - ESTRID HØGDALL
Direktør for Regionerner Bio-og GenomBank

Our third Podcast episode is out. In this episode, Sonia Diaz speaks to Estrid Høgdall from Herlev Hospital in Copenhagen, Denmark.

Estrid Høgdall is a Clinical Professor in Molecular Pathology at the University of Copenhagen and Head of the Molecular Unit, Department of Pathology at Herlev Hospital. Furthermore, She is also director of the National Biobank in Denmark covering regional cross-national infrastructure for biobanking.

In this episode, we’ll be talking about Danish biobanks and we will know among other interesting topics:
Why Denmark is unique in this field? Why are the biobanks so important for researchers? What is currently the most exciting thing happening in the genomics area....and the steps to follow to ensure patient confidentiality.

CIRCULAR VISION is a European Horizon 2020 FET-open project (by fostering novel ideas) and it is coordinated by PI Birgitte Regenberg who is an Associate Professor at the University of Copenhagen.

PODCAST: PROF. ANTONIO GASBARRINI AND FRANCO SCALDAFERRI

PROF. ANTONIO GASBARRINI AND FRANCO SCALDAFERRI

Second episode - BIRGITTE REGENBERG AND SONIA DIAZ TALK WITH
PROF. ANTONIO GASBARRINI AND FRANCO SCALDAFERRI

Our second Podcast episode is out. In this episode, we speak to Prof. Antonio Gasbarrini and Franco Scaldaferri from Gemelli Hospital in Rome, Italy. They join us to talk about their role and responsibilities in the CIRCULAR VISION project.

Inflammatory Bowel Disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), represent chronic disorders with a major health care impact, currently affecting ~3 million individuals in the EU.

Prof. Antonio Gasbarrini
Franco Scaldaferri

PODCAST: Prof. JULIA SIDENIUS JOHANSEN

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Julia Sidenius Johansen.jpg

BIRGITTE REGENBERG AND SONIA DIAZ TALK WITH

JULIA SIDENIUS JOHANSEN

On this podcast:

Pancreatic and lung cancer are among the most common causes of cancer deaths in Denmark and worldwide due to late diagnosis and lack of methods for specific treatment and recurrence tests.

The development of biomarkers for early detection as pursued in CIRCULAR VISION will dramatically change the health outcome of patients with pancreas and lung cancer since more patients will be radically operated and have a possibility for long time survival.

Our first Podcast episode 1 is out. In this episode, we speak to Julia Sidenius Johansen from Herlev/Gentofte Hospital in Denmark. Julia joins us to talk about her role and responsibilities in the Care DNA and CIRCULAR